PD146176 (NSC168807)
            目录号: A13347
    
            15-LO 抑制剂
    
								
							PD146176 (NSC168807) 是一种 15-脂氧合酶(15-LO)抑制剂,能够抑制兔网织红细胞的 15-LO,其抑制常数 Ki 为 197 nM。PD146176 (NSC168807) 在减少动脉粥样硬化方面具有显著效果。
        | Discription | PD146176 (NSC168807) is a 15-Lipoxygenase (15-LO) inhibitor, which inhibits rabbit reticulocyte 15-LO with a Ki of 197 nM. PD146176 (NSC168807) has a dramatic effect in reducing atherogenesis. | |||||
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| Cell Research | 
                            
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| 目录号 | A13347 | 
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| 分子式 | C15H11NS | 
| 分子量 | 237.32 | 
| CAS号 | 4079-26-9 | 
| SMILES | C1(N2)=C(CSC3=CC=CC=C31)C4=C2C=CC=C4 | 
| 其他名称 | PD 146176, PD-146176, NSC 168807, NSC-168807 | 
| 储存条件 | Store lyophilized at -20ºC, keep desiccated.   | 
				
| In vitro | DMSO | 40 mg/mL (168.54 mM) | |
| Water | Insoluble | ||
| Ethanol | 17 mg/mL | ||
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																	  *  <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.  | 
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg | 
|---|---|---|---|
| 0.1 mM | 42.14 mL | 210.69 mL | 421.37 mL | 
| 0.5 mM | 8.43 mL | 42.14 mL | 84.27 mL | 
| 1 mM | 4.21 mL | 21.07 mL | 42.14 mL | 
| 5 mM | 0.84 mL | 4.21 mL | 8.43 mL | 
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2