PD153035 (HCl salt)

目录号: A10702

EGFR inhibitor

PD153035 (HCl salt)

PD153035 (HCl salt) Chemical Structure

CAS NO. 183322-45-4

PD153035 is an extremely potent and specific inhibitor of the tyrosine kinase activity of EGFR.

库存: 现货

规格 价格 数量
10 mg
¥ 500.00
50 mg
¥ 2,200.00
100 mg
¥ 3,800.00
200 mg
¥ 6,300.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

PD153035 is an extremely potent and specific inhibitor of the tyrosine kinase activity of EGFR.
Targets
EGFR (Cell-free assay) EGFR (Cell-free assay)
5.2 pM(Ki)5.2 pM(Ki)
In vitro (25°C) DMSO 0.5 mg/mL (1.26 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% Propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.21 mL 126.04 mL 252.08 mL
0.5 mM 5.04 mL 25.21 mL 50.42 mL
1 mM 2.52 mL 12.6 mL 25.21 mL
5 mM 0.5 mL 2.52 mL 5.04 mL

*The above data is based on the productmolecular weight 396.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A10702
MECHANISM OF ACTION Inhibitor
M. Wt 396.7
Formula C16H14BrN3O2.HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 183322-45-4
Synonyms ZM 252868, AG 1517, Tyrphostin AG 1517, SU 5271, PD-153035
SMILES COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Br)OC.Cl

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