PD166866

Name: PD166866
SKU: A17161
Price: 140 CNY
Rating: 5 (288 reviews)

目录号: A17161

FGFR 抑制剂

PD166866 是一种 FGFR1 抑制剂，其 IC50 值为 55 nM，对 c-Src、PDGFR-b、EGFR 或胰岛素受体酪氨酸激酶以及 MEK、PKC 和 CDK4 没有影响。

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Grouped product items
规格	价格	库存
1mg	¥140.00	现货
2mg	¥210.00	现货
5mg	¥350.00	现货
10mg	¥560.00	现货
25mg	¥1,085.00	现货
50mg	¥2,100.00	现货
100mg	¥3,290.00	现货
*10mM 1mL in DMSO**	¥350.00	现货
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Data Sheet

SDS

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生物活性

Discription

PD166866 is a FGFR1 inhibitor with IC50 value of 55 nM, and no effect on c-Src, PDGFR-b, EGFR or insulin receptor tyrosine kinases or MEK, PKC, and CDK4.

Targets

Target	Value

产品信息

目录号	A17161
分子式	C20H24N6O3
分子量	396.44
CAS号	192705-79-6
SMILES	O=C(NC(C)(C)C)NC1=NC2=NC(N)=NC=C2C=C1C3=CC(OC)=CC(OC)=C3
其他名称	PD 166866, PD-166866
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	Warmed: 12 mg/mL (30.27 mM)
	Water	Insoluble
	Ethanol	Warmed: 3 mg/mL (7.56 mM)
In vivo	4% DMSO+30% PEG 300+2% Tween 80+ddH2O	3 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.22 mL	126.12 mL	252.24 mL
0.5 mM	5.04 mL	25.22 mL	50.45 mL
1 mM	2.52 mL	12.61 mL	25.22 mL
5 mM	0.5 mL	2.52 mL	5.04 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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