PD168393
目录号: A12725
EGFR 抑制剂
PD168393 是一种强效的、细胞渗透性的、不可逆的 EGFR 抑制剂,其 IC50 值为 700 pM。
| Discription | PD168393 is a potent, cell-permeable, irreversible inhibitor of EGFR with IC50 value of 700 pM. | |||||
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| Cell Research |
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| 目录号 | A12725 |
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| 分子式 | C17H13BrN4O |
| 分子量 | 369.22 |
| CAS号 | 194423-15-9 |
| SMILES | C=CC(=O)NC1=CC2=C(C=C1)N=CN=C2NC3=CC(=CC=C3)Br |
| 其他名称 | PD-168393, PD 168393 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | 72 mg/mL (195 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 30% PEG400+0.5% Tween80+5% propylene glycol | 9 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.08 mL | 135.42 mL | 270.84 mL |
| 0.5 mM | 5.42 mL | 27.08 mL | 54.17 mL |
| 1 mM | 2.71 mL | 13.54 mL | 27.08 mL |
| 5 mM | 0.54 mL | 2.71 mL | 5.42 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2