PD173074

目录号: A10703

FGFR1/VEGFR2 Inhibitor

PD173074 Chemical Structure

CAS NO. 219580-11-7

PD173074 is a potent, cell permeable and ATP competitive inhibitor of FGFR and VEGFR.

库存: 现货

规格 价格 数量
5 mg
¥ 300.00
10 mg
¥ 500.00
50 mg
¥ 1,400.00
100 mg
¥ 2,200.00
10mM * 1mL in DMSO
¥ 500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

PD173074 is a potent, cell permeable and ATP competitive inhibitor of FGFR and VEGFR.
Targets
Target Value
FGFR1IC50: ~25nM
VEGFR2IC50: 100nM-200nM
c-SrcIC50: 19.8μM
EGFRIC50: >50μM
Insulin ReceptorIC50: >50μM
MEKIC50: >50μM
PKCIC50: >50μM
In vitro DMSO 100 mg/mL (190.95 mM)
Water <1 mg/mL (<1 mM)
Ethanol 100 mg/mL (190.95 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.09 mL 95.47 mL 190.95 mL
0.5 mM 3.82 mL 19.09 mL 38.19 mL
1 mM 1.91 mL 9.55 mL 19.09 mL
5 mM 0.38 mL 1.91 mL 3.82 mL

*The above data is based on the productmolecular weight 523.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10703
MECHANISM OF ACTION Inhibitor
M. Wt 523.7
Formula C28H41N7O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 219580-11-7
Synonyms PD-173074
SMILES CCN(CC)CCCCNC1=NC2=NC(=C(C=C2C=N1)C3=CC(=CC(=C3)OC)OC)NC(=O)NC(C)(C)C

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