|MEK1 (Cell-free assay)||MEK2 (Cell-free assay)|
|17 nM||17 nM|
|In vitro (25°C)||DMSO||96 mg/mL (200.55 mM)|
|Water||<1 mg/mL (<1 mM)|
|Ethanol||14 mg/mL (29.24 mM)|
|In vivo||30% PEG400/0.5% Tween80/5% propylene glycol, pH 9||10 mg/mL|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||20.89 mL||104.45 mL||208.9 mL|
|0.5 mM||4.18 mL||20.89 mL||41.78 mL|
|1 mM||2.09 mL||10.44 mL||20.89 mL|
|5 mM||0.42 mL||2.09 mL||4.18 mL|
*The above data is based on the productmolecular weight 478.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|MECHANISM OF ACTION||Inhibitor|
|Storage||at -20°C 3 years Powder|
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