PD98059

目录号: A10705

MEK 抑制剂

PD98059

PD98059 Chemical Structure

CAS NO. 167869-21-8

PD98059是一种非ATP竞争性的MEK抑制剂,无细胞试验中IC50为2 μM,特异性抑制MEK-1介导的MAPK激活;不直接抑制ERK1或ERK2。

库存: 现货

规格 价格 数量
10 mg
¥ 500.00
50 mg
¥ 1,100.00
100 mg
¥ 1,900.00
200 mg
¥ 3,500.00
10mM * 1mL in DMSO
¥ 550.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

PD98059是一种非ATP竞争性的MEK抑制剂,无细胞试验中IC50为2 μM,特异性抑制MEK-1介导的MAPK激活;不直接抑制ERK1或ERK2。
靶点信息
MEK1 (Cell-free assay)
2 μM
In vitro (25°C) DMSO Warmed: 13 mg/mL (48.63 mM)
Water Insoluble
Ethanol Insoluble
In vivo 4% DMSO+30% PEG 300+5% Tween 80+ddH2O 1 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 37.41 mL 187.06 mL 374.11 mL
0.5 mM 7.48 mL 37.41 mL 74.82 mL
1 mM 3.74 mL 18.71 mL 37.41 mL
5 mM 0.75 mL 3.74 mL 7.48 mL

*The above data is based on the productmolecular weight 267.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10705
作用机制 Inhibitor (抑制剂)
M. Wt 267.3
Formula C16H13NO3
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 167869-21-8
SMILES COC1=CC=CC(=C1N)C2=CC(=O)C3=CC=CC=C3O2

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