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PDE5-IN-2

目录号: A19625
PDE5 抑制剂
PDE5-IN-2 是一种强效、高选择性、口服活性的 PDE5 抑制剂,IC50 为 0.31 nM,对 PDE2A、PDE10A、PDE4D2 和 PDE6C 的抑制作用较弱,其 IC50 分别为 106、46、43、1.2 nM。具有抗肺动脉高压活性。
Grouped product items
规格 价格 库存 数量
1mg
¥2,205.00
现货
5mg
¥6,685.00
现货
10mg
¥11,165.00
现货
25mg
¥13,755.00
现货
50mg
¥18,025.00
现货
100mg
¥23,765.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription PDE5-IN-2 is a potent, highly selective, and orally active PDE5 inhibitor, with an IC50 of 0.31 nM, less potently inhibits PDE2A, PDE10A, PDE4D2, and PDE6C, with IC50s of 106, 46, 43, 1.2 nM, respectively. Anti-pulmonary arterial hypertension activity.
Targets
Target Value
产品信息
目录号 A19625
分子式 C25H21N3O6S
分子量 491.52
CAS号 2244517-61-9
SMILES O=C1C2=C(C3=NC=CS3)NC(CC4=CC(OCO5)=C5C=C4)=C2OC6=CC(NCCOC)=CC(O)=C61
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

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