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PDK1 inhibitor

PDK1 抑制剂

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产品目录号: A16185


产品名 目录号 价格 数量
PDK1 inhibitor 2610 5mg A16185-5
¥ 800.00
PDK1 inhibitor 2610 10mg A16185-10
¥ 1,400.00
PDK1 inhibitor 2610 50mg A16185-50
¥ 5,500.00



PDK1 inhibitor, potent, ATP-competitive and selective dual PI3K and PDPK1 inhibitor (IC50 values 34 nM and 94 nM for PDK1 and p-T308-PKB inhibition, respectively.

PDK1 inhibitor




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Chemical Information

目录号 A16185
Mechanism of action Inhibitor
分子量 421.88
化学分子式 C25H15N5.HCl
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 853909-77-0
Synonyms N/A
SMILES code C1=CC(=CN=C1)C#CC2=CC3=C4C(=CN=C3C=C2)N=CN4C5=CC=C(C=C5)CC#N.Cl
化学名称 2-(4-(8-(pyridin-3-ylethynyl)-1H-imidazo[4,5-c]quinolin-1-yl)phenyl)acetonitrile hydrochloride


PDK1 inhibitor, potent, ATP-competitive and selective dual PI3K and PDPK1 inhibitor (IC50 values 34 nM and 94 nM for PDK1 and p-T308-PKB inhibition, respectively.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.7 mL 118.52 mL 237.03mL
0.5 mM 4.74 mL 23.7 mL 47.41 mL
1 mM 2.37 mL 11.85 mL 23.7 mL
5 mM 0.47 mL 2.37 mL 4.74 mL

*The above data is based on the productmolecular weight 421.88. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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