Peficitinib (ASP015K, JNJ-54781532)
目录号: A14438
JAK 抑制剂
Peficitinib 是一种新型强效的 JAK 抑制剂,在大鼠的佐剂诱导性关节炎模型中显示出强大的疗效。
JAK 抑制剂
Discription | Peficitinib is a novel potent JAK inhibitor, which demonstrated potent efficacy in adjuvant-induced arthritis model in rats. | ||
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Targets |
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目录号 | A14438 |
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分子式 | C18H22N4O2 |
分子量 | 326.39 |
CAS号 | 944118-01-8 |
SMILES | C1C2CC3CC(C2)(CC1C3NC4=C5C=CNC5=NC=C4C(=O)N)O |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 58 mg/mL (177.69 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 30.64 mL | 153.19 mL | 306.38 mL |
0.5 mM | 6.13 mL | 30.64 mL | 61.28 mL |
1 mM | 3.06 mL | 15.32 mL | 30.64 mL |
5 mM | 0.61 mL | 3.06 mL | 6.13 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2