Pexidartinib (PLX3397)

目录号: A15520

CSF1/Kit/FLT3 inhibitor

Pexidartinib (PLX3397) Chemical Structure

CAS NO. 1029044-16-3

Pexidartinib is a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potential antineoplastic activity.

库存: 现货

规格 价格 数量
10 mg
¥ 650.00
25 mg
¥ 1,000.00
50 mg
¥ 1,350.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Pexidartinib is a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potential antineoplastic activity.
Targets
Kit CSF-1R Flt3
10 nM20 nM160 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.93 mL 119.67 mL 239.34 mL
0.5 mM 4.79 mL 23.93 mL 47.87 mL
1 mM 2.39 mL 11.97 mL 23.93 mL
5 mM 0.48 mL 2.39 mL 4.79 mL

*The above data is based on the productmolecular weight 417.81. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A15520
MECHANISM OF ACTION Inhibitor
M. Wt 417.81
Formula C20H15ClF3N5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1029044-16-3
Synonyms PLX-3397, PLX 3397
SMILES FC(C1=CC=C(CNC2=NC=C(CC3=CNC4=NC=C(Cl)C=C43)C=C2)C=N1)(F)F

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