Pexmetinib (ARRY-614)

目录号: A10895

p38 MAPK inhibitor

Pexmetinib (ARRY-614)

Pexmetinib (ARRY-614) Chemical Structure

CAS NO. 945614-12-0

Pexmetinib is a potent inhibitor of cytokine synthesis, via the dual inhibition of p38 mitogen-activated protein kinase (MAPK), and Tie2/Tek receptor tyrosine kinase.

库存: 缺货

规格 价格
5 mg
¥ 900.00
10 mg
¥ 1,600.00
50 mg
¥ 4,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Pexmetinib is a potent inhibitor of cytokine synthesis, via the dual inhibition of p38 mitogen-activated protein kinase (MAPK), and Tie2/Tek receptor tyrosine kinase.
Targets
p38 MAPK Tie-2
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.97 mL 89.83 mL 179.65 mL
0.5 mM 3.59 mL 17.97 mL 35.93 mL
1 mM 1.8 mL 8.98 mL 17.97 mL
5 mM 0.36 mL 1.8 mL 3.59 mL

*The above data is based on the productmolecular weight 556.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A10895
MECHANISM OF ACTION Inhibitor
M. Wt 556.63
Formula C31H33FN6O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 945614-12-0
Synonyms ARRY614, ARRY 614
SMILES O=C(NCC1=CC(F)=CC=C1OC2=CC3=C(N(CCO)N=C3)C=C2)NC4=CC(C(C)(C)C)=NN4C5=CC=C(C)C=C5

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