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PF-03814735

目录号: A11171
Aurora A/B Kinase 抑制剂
PF-03814735 是一种新型、高效、可逆的 Aurora A/B 抑制剂,其 IC50 分别为 0.8 nM/5 nM,对 Flt3、FAK、TrkA 的抑制作用较弱,对 Met 和 FGFR1 几乎无活性。目前处于第一阶段临床试验。
Grouped product items
规格 价格 库存 数量
5mg
¥700.00
现货
10mg
¥1,120.00
现货
50mg
¥5,040.00
现货
100mg
¥8,750.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription PF-03814735 is a novel, potent and reversible inhibitor of Aurora A/B with IC50of 0.8 nM/5 nM, is less potent to Flt3, FAK, TrkA, and minimally active to Met and FGFR1. Phase 1.
Targets
Target Value
产品信息
目录号 A11171
分子式 C23H25F3N6O2
分子量 474.48
CAS号 942487-16-3
SMILES CC(=O)NCC(=O)N1[C@H]2CC[C@@H]1C3=C2C=CC(=C3)NC4=NC=C(C(=N4)NC5CCC5)C(F)(F)F
其他名称 PF03814735
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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