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PF-04217903 methanesulfonate

c-Met 抑制剂

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产品目录号: A15208

库存状态:中国现货中国现货

产品名 目录号 价格 数量
PF-04217903 methanesulfonate 5mg A15208-5
¥ 700.00
PF-04217903 methanesulfonate 10mg A15208-10
¥ 1,000.00
PF-04217903 methanesulfonate 50mg A15208-50
¥ 3,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

PF-04217903 methanesulfonate is a selective ATP-competitive c-Met inhibitor with IC50 of 4.8 nM, susceptible to oncogenic mutations (no activity to Y1230C mutant).

PF-04217903 methanesulfonate

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Chemical Information

目录号 A15208
Mechanism of action Inhibitor
分子量 468.49
化学分子式 C20H20N8O4S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 956906-93-7
Synonyms PF04217903 methanesulfonate, PF 04217903 methanesulfonate
SMILES code CS(=O)(=O)O.C1=CC2=C(C=CC(=C2)CN3C4=NC(=CN=C4N=N3)C5=CN(N=C5)CCO)N=C1
化学名称 methanesulfonic acid;2-[4-[3-(quinolin-6-ylmethyl)triazolo[4,5-b]pyrazin-5-yl]pyrazol-1-yl]ethanol

生物活性

Description
PF-04217903 methanesulfonate is a selective ATP-competitive c-Met inhibitor with IC50 of 4.8 nM, susceptible to oncogenic mutations (no activity to Y1230C mutant).

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.35 mL 106.73 mL 213.45mL
0.5 mM 4.27 mL 21.35 mL 42.69 mL
1 mM 2.13 mL 10.67 mL 21.35 mL
5 mM 0.43 mL 2.13 mL 4.27 mL

*The above data is based on the productmolecular weight 468.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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