PF-04217903 methanesulfonate
目录号: A15208
c-Met 抑制剂
PF-04217903 甲磺酸盐是一种选择性的 ATP 竞争性 c-Met 抑制剂,其 IC50 为 4.8 nM,对致癌突变敏感(对 Y1230C 突变体无活性)。
Discription | PF-04217903 methanesulfonate is a selective ATP-competitive c-Met inhibitor with IC50 of 4.8 nM, susceptible to oncogenic mutations (no activity to Y1230C mutant). |
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目录号 | A15208 |
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分子式 | C20H20N8O4S |
分子量 | 468.49 |
CAS号 | 956906-93-7 |
SMILES | CS(=O)(=O)O.C1=CC2=C(C=CC(=C2)CN3C4=NC(=CN=C4N=N3)C5=CN(N=C5)CCO)N=C1 |
其他名称 | PF04217903 methanesulfonate, PF 04217903 methanesulfonate |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2