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PF-04418948

EP2 Receptor 拮抗剂

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产品目录号: A12894

库存状态:中国现货中国现货

产品名 目录号 价格 数量
PF-04418948 10mg A12894-10
¥ 900.00
PF-04418948 25mg A12894-25
¥ 1,800.00
PF-04418948 50mg A12894-50
¥ 3,200.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

PF-04418948 is a potent and selective prostaglandin EP2 receptor antagonist with IC50 of 16 nM. Phase 1.

PF-04418948

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Chemical Information

目录号 A12894
Mechanism of action Antagonist
分子量 409.41
化学分子式 C23H20FNO5
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1078166-57-0
Synonyms PF04418948, PF 04418948
SMILES code O=C(C1(COC2=CC=C3C=C(OC)C=CC3=C2)CN(C(C4=CC=C(C=C4)F)=O)C1)O
化学名称 1-(4-fluorobenzoyl)-3-((6-methoxynaphthalen-2-yloxy)methyl)azetidine-3-carboxylic acid

生物活性

Description
PF-04418948 is a potent and selective prostaglandin EP2 receptor antagonist with IC50 of 16 nM. Phase 1.
Targets
EP2 receptor
16 nM

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.43 mL 122.13 mL 244.25mL
0.5 mM 4.89 mL 24.43 mL 48.85 mL
1 mM 2.44 mL 12.21 mL 24.43 mL
5 mM 0.49 mL 2.44 mL 4.89 mL

*The above data is based on the productmolecular weight 409.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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