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EP2 Receptor 拮抗剂

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产品目录号: A12894


产品名 目录号 价格 数量
PF-04418948 10mg A12894-10
¥ 900.00
PF-04418948 25mg A12894-25
¥ 1,800.00
PF-04418948 50mg A12894-50
¥ 3,200.00



PF-04418948 is a potent and selective prostaglandin EP2 receptor antagonist with IC50 of 16 nM. Phase 1.





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Chemical Information

目录号 A12894
Mechanism of action Antagonist
分子量 409.41
化学分子式 C23H20FNO5
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1078166-57-0
Synonyms PF04418948, PF 04418948
SMILES code O=C(C1(COC2=CC=C3C=C(OC)C=CC3=C2)CN(C(C4=CC=C(C=C4)F)=O)C1)O
化学名称 1-(4-fluorobenzoyl)-3-((6-methoxynaphthalen-2-yloxy)methyl)azetidine-3-carboxylic acid


PF-04418948 is a potent and selective prostaglandin EP2 receptor antagonist with IC50 of 16 nM. Phase 1.
EP2 receptor
16 nM


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.43 mL 122.13 mL 244.25mL
0.5 mM 4.89 mL 24.43 mL 48.85 mL
1 mM 2.44 mL 12.21 mL 24.43 mL
5 mM 0.49 mL 2.44 mL 4.89 mL

*The above data is based on the productmolecular weight 409.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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