PF-04449913

目录号: A13881

Smoothened inhibitor

PF-04449913

PF-04449913 Chemical Structure

CAS NO. 1095173-27-5

PF-04449913 is a potent and orally bioavailable inhibitor of smoothened.

库存: 现货

规格 价格 数量
5 mg
¥ 900.00
10 mg
¥ 1,600.00
25 mg
¥ 3,200.00
10mM * 1mL in DMSO
¥ 1,260.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

PF-04449913 is a potent and orally bioavailable inhibitor of smoothened.
Targets
Smoothened
5 nM
In vitro DMSO 47 mg/mL (125.52 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.73 mL 133.63 mL 267.25 mL
0.5 mM 5.35 mL 26.73 mL 53.45 mL
1 mM 2.67 mL 13.36 mL 26.73 mL
5 mM 0.53 mL 2.67 mL 5.35 mL

*The above data is based on the productmolecular weight 374.18. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A13881
MECHANISM OF ACTION Inhibitor
M. Wt 374.18
Formula C21H22N6O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1095173-27-5
Synonyms PF-4449913,PF04449913
SMILES CN1CC[C@H](C[C@@H]1C2=NC3=CC=CC=C3N2)NC(=O)NC4=CC=C(C=C4)C#N

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