Glasdegib (PF-04449913)

Name: Glasdegib (PF-04449913)
SKU: A13881
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A13881

Smoothened 抑制剂

PF-04449913 是一种强效且可口服生物利用度的抑制剂，针对smoothened。

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Grouped product items
规格	价格	库存
1mg	¥210.00	现货
5mg	¥560.00	现货
10mg	¥980.00	现货
25mg	¥2,170.00	现货
50mg	¥3,710.00	现货
100mg	¥5,390.00	现货
*10mM 1mL in DMSO**	¥630.00	现货
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Data Sheet

SDS

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生物活性

Discription

PF-04449913 is a potent and orally bioavailable inhibitor of smoothened.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A13881
分子式	C21H22N6O
分子量	374.18
CAS号	1095173-27-5
SMILES	CN1CC[C@H](C[C@@H]1C2=NC3=CC=CC=C3N2)NC(=O)NC4=CC=C(C=C4)C#N
其他名称	PF-4449913,PF04449913
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	46 mg/mL (122.85 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.73 mL	133.63 mL	267.25 mL
0.5 mM	5.35 mL	26.73 mL	53.45 mL
1 mM	2.67 mL	13.36 mL	26.73 mL
5 mM	0.53 mL	2.67 mL	5.35 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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