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PF-04457845

FAAH 抑制剂

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产品目录号: A15209

库存状态:中国现货中国现货

产品名 目录号 价格 数量
PF-04457845 5mg A15209-5
¥ 600.00
PF-04457845 10mg A15209-10
¥ 1,000.00
PF-04457845 50mg A15209-50
¥ 3,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

PF-04457845 is a potent and exquisitely selective inhibitor of FAAH, with an IC50 of 7.2 nM, and both analgesic and antiinflammatory effects in animal studies comparable to naproxen.

PF-04457845

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Chemical Information

目录号 A15209
Mechanism of action Inhibitor
分子量 455.43
化学分子式 C23H20F3N5O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1020315-31-4
Synonyms PF 04457845, PF04457845
SMILES code C1CN(CCC1=CC2=CC(=CC=C2)OC3=NC=C(C=C3)C(F)(F)F)C(=O)NC4=NN=CC=C4
化学名称 N-pyridazin-3-yl-4-[[3-[5-(trifluoromethyl)pyridin-2-yl]oxyphenyl]methylidene]piperidine-1-carboxamide

生物活性

Description
PF-04457845 is a potent and exquisitely selective inhibitor of FAAH, with an IC50 of 7.2 nM, and both analgesic and antiinflammatory effects in animal studies comparable to naproxen.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.96 mL 109.79 mL 219.57mL
0.5 mM 4.39 mL 21.96 mL 43.91 mL
1 mM 2.2 mL 10.98 mL 21.96 mL
5 mM 0.44 mL 2.2 mL 4.39 mL

*The above data is based on the productmolecular weight 455.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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