PF-04457845

目录号: A15209

FAAH 抑制剂

PF-04457845

PF-04457845 Chemical Structure

CAS NO. 1020315-31-4

PF-04457845是一种强效且选择性强的FAAH抑制剂,IC50为7.2 nM,在动物研究中的镇痛和抗炎作用均与萘普生相当。

库存: 现货

规格 价格 数量
5 mg
¥ 600.00
10 mg
¥ 1,000.00
50 mg
¥ 3,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

PF-04457845是一种强效且选择性强的FAAH抑制剂,IC50为7.2 nM,在动物研究中的镇痛和抗炎作用均与萘普生相当。
In vitro DMSO 90 mg/mL (197.61 mM)
Water Insoluble
Ethanol 4 mg/mL (8.78 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.96 mL 109.79 mL 219.57 mL
0.5 mM 4.39 mL 21.96 mL 43.91 mL
1 mM 2.2 mL 10.98 mL 21.96 mL
5 mM 0.44 mL 2.2 mL 4.39 mL

*The above data is based on the productmolecular weight 455.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A15209
作用机制 Inhibitor (抑制剂)
M. Wt 455.43
Formula C23H20F3N5O2
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1020315-31-4
Synonyms PF 04457845, PF04457845
SMILES C1CN(CCC1=CC2=CC(=CC=C2)OC3=NC=C(C=C3)C(F)(F)F)C(=O)NC4=NN=CC=C4

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