PF-04620110
目录号: A11526
DGAT1 抑制剂
PF-04620110 是一种口服活性、选择性和强效的二酰基甘油酰基转移酶-1(DGAT1)抑制剂,其半抑制浓度(IC50)为19 nM。
Discription | PF-04620110 is an orally active, selective and potent diglyceride acyltransferase-1 (DGAT1) inhibitor with IC50 of 19 nM. | |||||
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Targets |
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Cell Research |
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目录号 | A11526 |
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分子式 | C21H24N4O4 |
分子量 | 396.44 |
CAS号 | 1109276-89-2 |
SMILES | C1CC(CCC1CC(=O)O)C2=CC=C(C=C2)N3CCOC4=NC=NC(=C4C3=O)N |
其他名称 | PF04620110 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | Warmed: 46 mg/mL (116.03 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 25.22 mL | 126.12 mL | 252.24 mL |
0.5 mM | 5.04 mL | 25.22 mL | 50.45 mL |
1 mM | 2.52 mL | 12.61 mL | 25.22 mL |
5 mM | 0.5 mL | 2.52 mL | 5.04 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2