PF-04634817

Name: PF-04634817
SKU: A18659

目录号: A18659

CCR2 /CCR5 dual 拮抗剂

PF-04634817 Chemical Structure

CAS NO. 1228111-63-4

PF-04634817 is an orally administered CCR2 and CCR5 chemokine receptor antagonist, for the treatment of diabetic nephropathies and diabetic macular oedema.

库存：现货

规格	价格	数量
1 mg	￥ 700.00
5 mg	￥ 2,100.00
10 mg	￥ 3,800.00

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产品仅用于科学研究，不针对患者销售，望谅解.

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生物活性

PF-04634817 is an orally administered CCR2 and CCR5 chemokine receptor antagonist, for the treatment of diabetic nephropathies and diabetic macular oedema.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.55 mL	97.73 mL	195.47 mL
0.5 mM	3.91 mL	19.55 mL	39.09 mL
1 mM	1.95 mL	9.77 mL	19.55 mL
5 mM	0.39 mL	1.95 mL	3.91 mL

*The above data is based on the productmolecular weight 511.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A18659
作用机制	Antagonist (拮抗剂)
M. Wt	511.59
Formula	C25H36F3N5O3
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1228111-63-4
Synonyms	PF-04634817; PF 04634817; PF04634817; PF-4634817; PF 4634817; PF4634817.
SMILES	O=C([C@]1(C(C)C)C[C@H](N[C@@H]2[C@H](OC)COCC2)CC1)N3[C@](C4)([H])CN(C5=NC=NC(C(F)(F)F)=C5)[C@]4([H])C3