PF-04691502

目录号: A11024

PI3K/mTOR Inhibitor

PF-04691502 Chemical Structure

CAS NO. 1013101-36-4

PF-04691502 is a PI3K/mTOR kinase inhibitor, is also an agent targeting the phosphatidylinositol 3 kinase (PI3K) and mammalian target of rapamycin (mTOR) in the PI3K/mTOR signaling pathway.

库存: 现货

规格 价格 数量
5 mg
¥ 700.00
10 mg
¥ 1,200.00
50 mg
¥ 4,000.00
100 mg
¥ 7,200.00
10mM * 1mL in DMSO
¥ 850.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

PF-04691502 is a PI3K/mTOR kinase inhibitor, is also an agent targeting the phosphatidylinositol 3 kinase (PI3K) and mammalian target of rapamycin (mTOR) in the PI3K/mTOR signaling pathway.
Targets
Target Value
PI3Kδki: 1.6nM
PI3Kαki: 1.8nM
PI3Kγki: 1.9nM
PI3Kβki: 2.1nM
P-Akt(S473)IC50: 3.8nM
P-Akt(T308)IC50: 7.5nM
mTORki: 16nM
In vitro DMSO 14 mg/mL (32.9 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.5 mL 117.51 mL 235.02 mL
0.5 mM 4.7 mL 23.5 mL 47 mL
1 mM 2.35 mL 11.75 mL 23.5 mL
5 mM 0.47 mL 2.35 mL 4.7 mL

*The above data is based on the productmolecular weight 425.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11024
MECHANISM OF ACTION Inhibitor
M. Wt 425.5
Formula C22H27N5O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1013101-36-4
Synonyms PF04691502
SMILES CC1=C2C=C(C(=O)N(C2=NC(=N1)N)C3CCC(CC3)OCCO)C4=CN=C(C=C4)OC

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