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RAF 抑制剂

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产品目录号: A12739


产品名 目录号 价格 数量
PF-04880594 5mg A12739-5
¥ 3,500.00
PF-04880594 10mg A12739-10
¥ 6,500.00
PF-04880594 25mg A12739-25
¥ 12,000.00
PF-04880594 50mg A12739-50
¥ 20,000.00



PF-04880594 is an inhibitor of RAF with IC50 values of 0.19 nM/0.13 nM and 0.39 nM for BRAF/BRAFV599E and c-RAF, respectively.





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Chemical Information

目录号 A12739
Mechanism of action Inhibitor
分子量 394.38
化学分子式 C19H16F2N8
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1111636-35-1
Synonyms PF-04880594, PF04880594, PF 04880594
化学名称 3-((4-(1-(2,2-difluoroethyl)-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazol-4-yl)pyrimidin-2-yl)amino)propanenitrile


PF-04880594 is an inhibitor of RAF with IC50 values of 0.19 nM/0.13 nM and 0.39 nM for BRAF/BRAFV599E and c-RAF, respectively.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.36 mL 126.78 mL 253.56mL
0.5 mM 5.07 mL 25.36 mL 50.71 mL
1 mM 2.54 mL 12.68 mL 25.36 mL
5 mM 0.51 mL 2.54 mL 5.07 mL

*The above data is based on the productmolecular weight 394.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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