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PF-04929113 (SNX-5422)

Hsp90 抑制剂

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产品目录号: A11074


产品名 目录号 价格 数量
PF-04929113 5mg A11074-5
¥ 1,500.00
PF-04929113 10mg A11074-10
¥ 2,800.00
PF-04929113 50mg A11074-50
¥ 6,000.00
PF-04929113 100mg A11074-100
¥ 10,500.00
PF-04929113 (SNX-5422) 10mM * 1mL in DMSO A11074-10mM-D
¥ 2,150.00



PF-04929113 (SNX-5422) is orally bioavailable heat shock protein 90 (Hsp90) inhibitor.

PF-04929113 (SNX-5422)




顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 PF-04929113 (SNX-5422) 发表的文献 (1)
  • Hiroki Murano, .et al. A purine-type heat shock protein 90 inhibitor promotes the heat shock response in Arabidopsis, Plant Biotechnol Rep, 2017, 11:107每113

Chemical Information

目录号 A11074
Mechanism of action Inhibitor
分子量 521.5
化学分子式 C25H30F3N5O4
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 908115-27-5
Synonyms PF04929113, SNX5422
SMILES code CC1(CC2=C(C(=O)C1)C(=NN2C3=CC(=C(C=C3)C(=O)N)NC4CCC(CC4)OC(=O)CN)C(F)(F)F)C
化学名称 (1r,4r)-4-((2-carbamoyl-5-(6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)phenyl)amino)cyclohexyl 2-aminoacetate


PF-04929113 (SNX-5422) is orally bioavailable heat shock protein 90 (Hsp90) inhibitor.
37 nM41 nM(Kd)


Solubility (25°C) * In vitro DMSO 104 mg/mL (199.41 mM)
Water <1 mg/mL (<1 mM)
Ethanol 5 mg/mL (9.58 mM)
In vivo 0.5% CMC/0.25% Tween 80 25 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.18 mL 95.88 mL 191.75mL
0.5 mM 3.84 mL 19.18 mL 38.35 mL
1 mM 1.92 mL 9.59 mL 19.18 mL
5 mM 0.38 mL 1.92 mL 3.84 mL

*The above data is based on the productmolecular weight 521.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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