PF-05175157

Name: PF-05175157
SKU: A21460

目录号: A21460

ACC inhibitor

PF-05175157 Chemical Structure

CAS NO. 1301214-47-0

PF-05175157 is broad spectrum acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 27.0, 33.0, 23.5 and 50.4 nM for ACC1 (human), ACC2 (human), ACC1 (rat), ACC2 (rat), respectively.

库存：现货

规格	价格	数量
5 mg	￥ 630.00
10 mg	￥ 1,090.00
50 mg	￥ 3,220.00
100 mg	￥ 6,440.00

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生物活性

PF-05175157 is broad spectrum acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 27.0, 33.0, 23.5 and 50.4 nM for ACC1 (human), ACC2 (human), ACC1 (rat), ACC2 (rat), respectively.

溶解度 *

In vitro	DMSO	28 mg/mL (69.05 mM)
	* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.66 mL	123.31 mL	246.62 mL
0.5 mM	4.93 mL	24.66 mL	49.32 mL
1 mM	2.47 mL	12.33 mL	24.66 mL
5 mM	0.49 mL	2.47 mL	4.93 mL

*The above data is based on the productmolecular weight 405.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A21460
作用机制	Inhibitor (抑制剂)
M. Wt	405.49
Formula	C23H27N5O2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1301214-47-0
Synonyms	PF05175157, PF 05175157
SMILES	O=C1CC2(CCN(C(C3=CC=C4C(NC(C)=N4)=C3)=O)CC2)CC5=C1N(C(C)C)N=C5