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PF-06250112

目录号: A18612
BTK 抑制剂
PF-06250112 是一种高效、高选择性、口服生物利用度的 BTK 抑制剂,其 IC50 为 0.5 nM,对 BMX 非受体酪氨酸激酶和 TEC 显示出抑制效果,其 IC50 分别为 0.9 nM 和 1.2 nM。
Grouped product items
规格 价格 库存 数量
5mg
¥3,640.00
现货
10mg
¥6,440.00
现货
25mg
¥13,755.00
现货
50mg
¥17,360.00
现货
100mg
¥23,765.00
现货
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生物活性
Discription PF-06250112 is a potent, highly selective, orally bioavailable BTK inhibitor with an IC50 of 0.5 nM, shows inhibitory effect toward BMX nonreceptor tyrosine kinase and TEC with IC50s of 0.9 nM and 1.2 nM, respectively.
产品信息
目录号 A18612
分子式 C22H20F2N6O2
分子量 438.43
CAS号 1609465-89-5
SMILES O=C(N)C1=C(N(N=C1C2=CC=C(C=C2)OC3=CC=C(C=C3F)F)[C@@H]4CN(CCC4)C#N)N
其他名称 PF06250112, PF 06250112
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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