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PF-06273340

PF-06273340

Name: PF-06273340
SKU: A22377

目录号: A22377

pan-Trk inhibitor

PF-06273340 Chemical Structure

CAS NO. 1402438-74-7

PF-06273340 is a highly potent, kinases elective, well-tolerated pan-Trk inhibitor with IC50 values of 6, 4, 3 nM for TrkA, TrkB, Trk C, respectively.

库存：现货

规格	价格	数量
10 mg	￥ 1,140.00
25 mg	￥ 2,290.00
50 mg	￥ 3,940.00
100 mg	￥ 6,730.00

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生物活性

PF-06273340 is a highly potent, kinases elective, well-tolerated pan-Trk inhibitor with IC50 values of 6, 4, 3 nM for TrkA, TrkB, Trk C, respectively.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.84 mL	104.18 mL	208.37 mL
0.5 mM	4.17 mL	20.84 mL	41.67 mL
1 mM	2.08 mL	10.42 mL	20.84 mL
5 mM	0.42 mL	2.08 mL	4.17 mL

*The above data is based on the productmolecular weight 479.92. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A22377
M. Wt	479.92
Formula	C23H22ClN7O3
Solubility	DMSO
Purity	>98%
Storage	at -20°C 2 years
CAS No.	1402438-74-7
Synonyms	PF06273340,PF 06273340
SMILES	CC(C)(CO)N1C=C(C2=CN=C(N=C21)N)C(=O)C3=CC(=CN=C3)NC(=O)CC4=NC=C(C=C4