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PF-06305591

PF-06305591

Name: PF-06305591
SKU: A18748

目录号: A18748

NaV1.8 blocker

PF-06305591 Chemical Structure

CAS NO. 1449473-97-5

PF-06305591 is a potent and highly selective voltage gated sodium channel NaV1.8 blocker, with an IC50 of 15 nM. An excellent preclinical in vitro ADME and safety profile.

库存：现货

规格	价格	数量
5 mg	￥ 1,600.00
10 mg	￥ 2,800.00
50 mg	￥ 9,800.00

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产品仅用于科学研究，不针对患者销售，望谅解.

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生物活性

PF-06305591 is a potent and highly selective voltage gated sodium channel NaV1.8 blocker, with an IC50 of 15 nM. An excellent preclinical in vitro ADME and safety profile.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	36.45 mL	182.24 mL	364.48 mL
0.5 mM	7.29 mL	36.45 mL	72.9 mL
1 mM	3.64 mL	18.22 mL	36.45 mL
5 mM	0.73 mL	3.64 mL	7.29 mL

*The above data is based on the productmolecular weight 274.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A18748
作用机制	Blocker (阻断剂)
M. Wt	274.36
Formula	C15H22N4O
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1449473-97-5
Synonyms	PF06305591, PF 06305591
SMILES	CC(C)(C)C1=CC=C(NC([C@H]([C@@H](C)C(N)=O)N)=N2)C2=C1