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PF-06424439

PF-06424439

Name: PF-06424439
SKU: A12608

目录号: A12608

DGAT2 inhibitor

PF-06424439 Chemical Structure

CAS NO. 1469284-78-3

PF-06424439 is an oral, potent and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 of 14 nM.

库存：现货

规格	价格	数量
1 mg	￥ 3,200.00
5 mg	￥ 9,600.00
10 mg	￥ 16,000.00

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生物活性

PF-06424439 is an oral, potent and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 of 14 nM.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.73 mL	113.65 mL	227.3 mL
0.5 mM	4.55 mL	22.73 mL	45.46 mL
1 mM	2.27 mL	11.37 mL	22.73 mL
5 mM	0.45 mL	2.27 mL	4.55 mL

*The above data is based on the productmolecular weight 439.94. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A12608
作用机制	Inhibitor (抑制剂)
M. Wt	439.94
Formula	C22H26ClN7O
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1469284-78-3
Synonyms	PF06424439, PF 06424439
SMILES	O=C([C@H]1CN(C2=CC=C3C(NC(C4(N5N=CC(Cl)=C5)CC4)=N3)=N2)CCC1)N6CCCC6