PF-06447475

Name: PF-06447475
SKU: A15504
Price: 245 CNY
Rating: 5 (288 reviews)

目录号: A15504

LRRK2 抑制剂

PF-06447475 是一种高效、选择性的、能穿透大脑的 LRRK2 抑制剂，其 IC50 分别针对 Wt LRRK2 和 G2019S LRRK2 为 3 nM/11 nM。

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Grouped product items
规格	价格	库存
5mg	¥245.00	现货
10mg	¥385.00	现货
25mg	¥560.00	现货
50mg	¥875.00	现货
100mg	¥1,540.00	现货
200mg	¥2,730.00	现货
*10mM 1mL in DMSO**	¥280.00	现货
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Data Sheet

SDS

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生物活性

Discription

PF-06447475 is a highly potent, selective, brain penetrant LRRK2 inhibitor with IC50 of 3 nM/11 nM for Wt LRRK2/G2019S LRRK2 respectively.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A15504
分子式	C17H15N5O
分子量	305.33
CAS号	1527473-33-1
SMILES	C1COCCN1C2=NC=NC3=C2C(=CN3)C4=CC=CC(=C4)C#N
其他名称	PF06447475, PF 06447475
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	56 mg/mL (183.4 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	32.75 mL	163.76 mL	327.51 mL
0.5 mM	6.55 mL	32.75 mL	65.5 mL
1 mM	3.28 mL	16.38 mL	32.75 mL
5 mM	0.66 mL	3.28 mL	6.55 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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