PF-06447475

目录号: A15504

LRRK2 inhibitor

PF-06447475

PF-06447475 Chemical Structure

CAS NO. 1527473-33-1

PF-06447475 is a highly potent, selective, brain penetrant LRRK2 inhibitor with IC50 of 3 nM/11 nM for Wt LRRK2/G2019S LRRK2 respectively.

库存: 现货

规格 价格 数量
10 mg
¥ 1,000.00
25 mg
¥ 2,000.00
50 mg
¥ 4,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

PF-06447475 is a highly potent, selective, brain penetrant LRRK2 inhibitor with IC50 of 3 nM/11 nM for Wt LRRK2/G2019S LRRK2 respectively.
Targets
LRRK2 G2019S LRRK2
3nM11nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 32.75 mL 163.76 mL 327.51 mL
0.5 mM 6.55 mL 32.75 mL 65.5 mL
1 mM 3.28 mL 16.38 mL 32.75 mL
5 mM 0.66 mL 3.28 mL 6.55 mL

*The above data is based on the productmolecular weight 305.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A15504
MECHANISM OF ACTION Inhibitor
M. Wt 305.33
Formula C17H15N5O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1527473-33-1
Synonyms PF06447475, PF 06447475
SMILES C1COCCN1C2=NC=NC3=C2C(=CN3)C4=CC=CC(=C4)C#N

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