PF-06751979

Name: PF-06751979
SKU: A20066

目录号: A20066

BACE1 inhibitor

PF-06751979 Chemical Structure

CAS NO. 1818339-66-0

PF-06751979 is a potent, brain penetrant, β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor with an IC50 of 7.3 nM in BACE1 binding assay.

库存：现货

规格	价格	数量
5 mg	￥ 3,500.00
10 mg	￥ 5,500.00
50 mg	￥ 18,000.00
100 mg	￥ 25,000.00

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产品仅用于科学研究，不针对患者销售，望谅解.

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生物活性

PF-06751979 is a potent, brain penetrant, β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor with an IC50 of 7.3 nM in BACE1 binding assay.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.95 mL	109.77 mL	219.54 mL
0.5 mM	4.39 mL	21.95 mL	43.91 mL
1 mM	2.2 mL	10.98 mL	21.95 mL
5 mM	0.44 mL	2.2 mL	4.39 mL

*The above data is based on the productmolecular weight 455.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A20066
作用机制	Inhibitor (抑制剂)
M. Wt	455.5
Formula	C18H19F2N5O3S2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1818339-66-0
Synonyms	PF 06751979, PF06751979
SMILES	FC(F)OC1=CN=C(C(NC2=CSC([C@]34CO[C@@H](C)C[C@@]3([H])CSC(N)=N4)=N2)=O)C=C1