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PF-06821497

目录号: A21388
EZH2 抑制剂
PF-06821497(化合物23a)是一种强效、选择性且可口服的增强子泽斯特同源物2(EZH2)抑制剂,对突变型Y641N EZH2的Ki值<0.1 nM。展示出强大的肿瘤生长抑制效果。
Grouped product items
规格 价格 库存 数量
1mg
¥630.00
现货
5mg
¥1,610.00
现货
10mg
¥2,555.00
现货
25mg
¥3,885.00
现货
50mg
¥5,460.00
现货
100mg
¥6,860.00
现货
10mM * 1mL in DMSO
¥1,470.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription PF-06821497 (compound 23a) is a potent, selective and orally active Enhancer of Zeste Homolog 2 (EZH2) inhibitor, with a Ki value <0.1 nM against mutant Y641N EZH2. Exhibits robust tumor growth inhibition.
产品信息
目录号 A21388
分子式 C22H24Cl2N2O5
分子量 467.34
CAS号 1844849-10-0
SMILES COC1=C(CN2CCC(C(Cl)=CC([C@H](OC)C3COC3)=C4Cl)=C4C2=O)C(NC(C)=C1)=O
其他名称 PF06821497, PF 06821497
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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