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PF-06855800 (PF06855800)是一种有效的，选择性的，SAM竞争性，BBB渗透性，口服活性的蛋白精氨酸甲基转移酶PRMT5抑制剂，Ki为0.02 nM。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.46 mL | 127.29 mL | 254.58 mL |
| 0.5 mM | 5.09 mL | 25.46 mL | 50.92 mL |
| 1 mM | 2.55 mL | 12.73 mL | 25.46 mL |
| 5 mM | 0.51 mL | 2.55 mL | 5.09 mL |
*The above data is based on the productmolecular weight 392.811. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16860 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 392.811 |
| Formula | C17H16ClFN4O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1989620-04-3 |
| Synonyms | PF06855800, PF 06855800 |
| SMILES | NC1=C2C(N([C@H]3[C@@H]([C@@H]([C@@H]([C@@H](C4=CC=C(Cl)C(F)=C4)O)O3)O)O)C=C2)=NC=N1 |
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