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PF-06873600是一种口服生物利用型，细胞周期蛋白依赖性激酶（CDK）抑制剂，其对 CDK2、CDK4和CDK6的Ki值分别为 0.09 nM、0.13 nM 和 0.16 nM。具有潜在的抗肿瘤活性。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.21 mL | 106.04 mL | 212.08 mL |
| 0.5 mM | 4.24 mL | 21.21 mL | 42.42 mL |
| 1 mM | 2.12 mL | 10.6 mL | 21.21 mL |
| 5 mM | 0.42 mL | 2.12 mL | 4.24 mL |
*The above data is based on the productmolecular weight 471.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16875 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 471.52 |
| Formula | C20H27F2N5O4S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 2185857-97-8 |
| Synonyms | PF 06873600, PF06873600 |
| SMILES | O=C1C(C(F)F)=CC2=CN=C(NC3CCN(S(=O)(C)=O)CC3)N=C2N1[C@H]4[C@](C)(O)CCC4 |
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