目录号: A11183
FAAH 抑制剂
PF-3845 是一种强效、选择性且不可逆的 FAAH 抑制剂(Ki = 0.23 μM)。它通过依赖 大麻素受体 的机制减轻炎症性疼痛。
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生物活性
| Discription | PF-3845 is a potent, selective, and irreversible inhibitor of FAAH (Ki = 0.23 μM). It reduces inflammatory pain via a cannabinoid receptor-dependent mechanism. |
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产品信息
| 目录号 | A11183 |
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| 分子式 | C24H23F3N4O2 |
| 分子量 | 456.46 |
| CAS号 | 1196109-52-0 |
| SMILES | C1CN(CCC1CC2=CC(=CC=C2)OC3=NC=C(C=C3)C(F)(F)F)C(=O)NC4=CN=CC=C4 |
| 其他名称 | PF3845 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 87 mg/mL (190.6 mM) | |
| Water | Insoluble | ||
| Ethanol | 87 mg/mL (190.6 mM) | ||
| In vivo | 30% propylene glycol, 5% Tween 80, 65% D5W | 14 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.91 mL | 109.54 mL | 219.08 mL |
| 0.5 mM | 4.38 mL | 21.91 mL | 43.82 mL |
| 1 mM | 2.19 mL | 10.95 mL | 21.91 mL |
| 5 mM | 0.44 mL | 2.19 mL | 4.38 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1196109-52-0 | 1196109-52-0 供应商 | 1196109-52-0 花费 | 1196109-52-0 生产商 | 订购 1196109-52-0 | 1196109-52-0 代理商

















