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PF-4191834

PF-4191834

Name: PF-4191834
SKU: A18777

目录号: A18777

5-LOX inhibitor

PF-4191834 Chemical Structure

CAS NO. 1029317-21-2

PF-4191834 is a novel, potent and selective non-redox 5-lipoxygenase inhibitor effective in inflammation and pain with an IC50=229 nM. displays ~300-fold selectivity for 5-LOX over 12-LOX and 15-LOX, shows no activity toward the cyclooxygenase enzymes.

库存：现货

规格	价格	数量
1 mg	￥ 2,200.00
5 mg	￥ 6,200.00
10 mg	￥ 11,000.00

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.41 mL	127.06 mL	254.12 mL
0.5 mM	5.08 mL	25.41 mL	50.82 mL
1 mM	2.54 mL	12.71 mL	25.41 mL
5 mM	0.51 mL	2.54 mL	5.08 mL

*The above data is based on the productmolecular weight 393.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A18777
作用机制	Inhibitor (抑制剂)
M. Wt	393.51
Formula	C22H23N3O2S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1029317-21-2
Synonyms	PF-04191834; PF04191834; PF 04191834; PF-4191834; PF4191834; PF 4191834.
SMILES	O=C(C1(C2=CC=CC(SC3=CC=C(C4=CC=NN4C)C=C3)=C2)CCOCC1)N