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PF 429242

促销

SREBP 抑制剂

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产品目录号: A11230

库存状态:中国现货中国现货

产品名 目录号 价格 数量
PF 429242 10mg A11230-10
¥ 800.00
PF 429242 25mg A11230-25
¥ 1,800.00
PF 429242 50mg A11230-50
¥ 3,000.00
PF 429242 100mg A11230-100
¥ 5,500.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

PF 429242 is a reversible, competitive inhibitor of sterol regulatory element-binding protein (SREBP) site 1 protease.

PF 429242

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顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 PF 429242 发表的文献 (4)
  • Hui Fang, .et al. (Pro)renin receptor mediates albumin-induced cellular responses: role of site-1 protease-derived soluble (pro)renin receptor in renal epithelial cells, Am J Physiol Cell Physiol, 2017, Dec 1; 313(6): C632每C643 PMID: 28903918
  • Tsutomu Nakagawa, .et al. Site-1 protease is required for the generation of soluble (pro)renin receptor, J Biochem, 2016, Apr 1;161(4):369-379 PMID: 28013223
  • Shimada S, .et al. Therapeutic effect of post-exposure treatment with antiserum on severe fever with thrombocytopenia syndrome (SFTS) in a mouse model of SFTS virus infection, Virology, 2015, Aug;482:19-27 PMID: 25817401
  • Jan H. Reiling, .et al. A Luman/CREB3每ADP-ribosylation factor 4 (ARF4) signaling pathway mediates the response to Golgi stress and susceptibility to pathogens, Nat Cell Biol., 2013, 15(12): 1473每1485. PMID: 24185178

Chemical Information

目录号 A11230
Mechanism of action Inhibitor
分子量 409.56
化学分子式 C25H35N3O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 947303-87-9
Synonyms PF-429242, PF429242
SMILES code CCN(CC)CC1=CC=C(C=C1)C(=O)N(CCC2=CC=CC=C2OC)[C@@H]3CCNC3
化学名称 4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide

生物活性

Description
PF 429242 is a reversible, competitive inhibitor of sterol regulatory element-binding protein (SREBP) site 1 protease.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.42 mL 122.08 mL 244.16mL
0.5 mM 4.88 mL 24.42 mL 48.83 mL
1 mM 2.44 mL 12.21 mL 24.42 mL
5 mM 0.49 mL 2.44 mL 4.88 mL

*The above data is based on the productmolecular weight 409.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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