PF 431396

目录号: A11142

FAK/PYK2 抑制剂

PF 431396

PF 431396 Chemical Structure

CAS NO. 717906-29-1

PF 431396是一种双粘着斑激酶(FAK)和富含脯氨酸的酪氨酸激酶2(PYK2)抑制剂(IC50值分别为2和11 nM)。

库存: 现货

规格 价格 数量
10 mg
¥ 800.00
25 mg
¥ 1,600.00
50 mg
¥ 2,800.00
100 mg
¥ 4,800.00
10mM * 1mL in DMSO
¥ 1,050.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

PF 431396是一种双粘着斑激酶(FAK)和富含脯氨酸的酪氨酸激酶2(PYK2)抑制剂(IC50值分别为2和11 nM)。
靶点信息
FAK PYK2
2 nM11 nM
In vitro DMSO 100 mg/mL (197.43 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.74 mL 98.72 mL 197.43 mL
0.5 mM 3.95 mL 19.74 mL 39.49 mL
1 mM 1.97 mL 9.87 mL 19.74 mL
5 mM 0.39 mL 1.97 mL 3.95 mL

*The above data is based on the productmolecular weight 506.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11142
作用机制 Inhibitor (抑制剂)
M. Wt 506.5
Formula C22H21F3N6O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 717906-29-1
Synonyms PF-431396
SMILES CN(C1=CC=CC=C1CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)C4)S(=O)(=O)C

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