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PYK2/FAK 抑制剂

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产品目录号: A13461


产品名 目录号 价格 数量
PF-4618433 5mg A13461-5
¥ 3,000.00
PF-4618433 10mg A13461-10
¥ 5,200.00
PF-4618433 25mg A13461-25
¥ 11,000.00



PF-4618433 shows improved PYK2 potency, reduced p38 activity, and superior overall selectivity relative to the prototype BIRB796.





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Chemical Information

目录号 A13461
Mechanism of action Inhibitor
分子量 445.52
化学分子式 C24H27N7O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1166393-85-6
Synonyms PF 4618433, PF4618433
SMILES code Cc1ccc(cc1)n2c(cc(n2)C(C)(C)C)NC(=O)Nc3cc(n[nH]3)COc4cccnc4
化学名称 N-[3-(tert-butyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N'-[3-[(pyridin-3-yloxy)methyl]pyrazol-5-yl]urea


PF-4618433 shows improved PYK2 potency, reduced p38 activity, and superior overall selectivity relative to the prototype BIRB796.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.45 mL 112.23 mL 224.46mL
0.5 mM 4.49 mL 22.45 mL 44.89 mL
1 mM 2.24 mL 11.22 mL 22.45 mL
5 mM 0.45 mL 2.24 mL 4.49 mL

*The above data is based on the productmolecular weight 445.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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