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PF-4618433

PYK2/FAK 抑制剂

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产品目录号: A13461

库存状态:中国现货中国现货

产品名 目录号 价格 数量
PF-4618433 5mg A13461-5
¥ 3,000.00
PF-4618433 10mg A13461-10
¥ 5,200.00
PF-4618433 25mg A13461-25
¥ 11,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

PF-4618433 shows improved PYK2 potency, reduced p38 activity, and superior overall selectivity relative to the prototype BIRB796.

PF-4618433

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Chemical Information

目录号 A13461
Mechanism of action Inhibitor
分子量 445.52
化学分子式 C24H27N7O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1166393-85-6
Synonyms PF 4618433, PF4618433
SMILES code Cc1ccc(cc1)n2c(cc(n2)C(C)(C)C)NC(=O)Nc3cc(n[nH]3)COc4cccnc4
化学名称 N-[3-(tert-butyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N'-[3-[(pyridin-3-yloxy)methyl]pyrazol-5-yl]urea

生物活性

Description
PF-4618433 shows improved PYK2 potency, reduced p38 activity, and superior overall selectivity relative to the prototype BIRB796.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.45 mL 112.23 mL 224.46mL
0.5 mM 4.49 mL 22.45 mL 44.89 mL
1 mM 2.24 mL 11.22 mL 22.45 mL
5 mM 0.45 mL 2.24 mL 4.49 mL

*The above data is based on the productmolecular weight 445.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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