PF 477736

Name: PF 477736
SKU: A11520
Price: 245 CNY
Rating: 5 (288 reviews)

目录号: A11520

Chk 抑制剂

PF 477736 是一种选择性的检查点激酶 1 (Chk1) 抑制剂（对 Chk1 和 Chk2 的 Ki 值分别为 0.49 nM 和 47 nM）。

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Grouped product items
规格	价格	库存
1mg	¥245.00	现货
2mg	¥280.00	现货
5mg	¥455.00	现货
10mg	¥840.00	现货
25mg	¥1,540.00	现货
50mg	¥2,940.00	现货
*10mM 1mL in DMSO**	¥490.00	现货
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Data Sheet

SDS

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生物活性

Discription

PF 477736 is a selective checkpoint kinase 1 (Chk1) inhibitor (Ki values are 0.49 and 47 nM for Chk1 and Chk2 respectively).

Targets

Target	Value

产品信息

目录号	A11520
分子式	C22H25N7O2
分子量	419.48
CAS号	952021-60-2
SMILES	CN1C=C(C=N1)C2=NC3=C4C2=CNNC(=O)C4=CC(=C3)NC(=O)[C@@H](C5CCCCC5)N
其他名称	PF-0044736, PF0044736
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	5 mg/mL (11.92 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	2% DMSO+40% PEG 300	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.84 mL	119.2 mL	238.39 mL
0.5 mM	4.77 mL	23.84 mL	47.68 mL
1 mM	2.38 mL	11.92 mL	23.84 mL
5 mM	0.48 mL	2.38 mL	4.77 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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