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PF-4840154是TrpA1通道的非亲电参考激动剂。基于TRPA1敲除小鼠在某些临床前发展模型中显示出几乎完全减轻了疼痛行为的事实，因此认为TRPA1通道是有吸引力的疼痛靶标。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.43 mL | 107.15 mL | 214.3 mL |
| 0.5 mM | 4.29 mL | 21.43 mL | 42.86 mL |
| 1 mM | 2.14 mL | 10.72 mL | 21.43 mL |
| 5 mM | 0.43 mL | 2.14 mL | 4.29 mL |
*The above data is based on the productmolecular weight 466.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13996 |
|---|---|
| 作用机制 | Agonist (激动剂) |
| M. Wt | 466.63 |
| Formula | C26H38N6O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1332708-14-1 |
| Synonyms | PF 4840154, PF4840154. |
| SMILES | O=C(C1=CN=C(N2CCN(CC3COCCC3)CC2)N=C1NCC(C)C)NCC4=CC=CC=C4 |
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