PF-4989216

目录号: A12889

PI3K inhibitor

PF-4989216 Chemical Structure

CAS NO. 1276553-09-3

PF-4989216 is a potent and selective PI3K inhibitor with IC50 of 2 nM, 142 nM, 65 nM, 1 nM, and 110 nM for p110??, p110??, p110??, p110??, and VPS34, respectively.

库存: 现货

规格 价格 数量
5 mg
¥ 1,050.00
10 mg
¥ 1,700.00
25 mg
¥ 3,200.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

PF-4989216 is a potent and selective PI3K inhibitor with IC50 of 2 nM, 142 nM, 65 nM, 1 nM, and 110 nM for p110??, p110??, p110??, p110??, and VPS34, respectively.
靶点信息
p110δ p110α p110γ Vps34 p110β
1 nM2 nM65 nM110 nM142 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.29 mL 131.44 mL 262.88 mL
0.5 mM 5.26 mL 26.29 mL 52.58 mL
1 mM 2.63 mL 13.14 mL 26.29 mL
5 mM 0.53 mL 2.63 mL 5.26 mL

*The above data is based on the productmolecular weight 380.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12889
MECHANISM OF ACTION Inhibitor
M. Wt 380.4
Formula C18H13FN6OS
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1276553-09-3
Synonyms PF4989216, PF 4989216
SMILES C1COCCN1C2=C(C(=C(S2)C3=NC=NN3)C4=C(C=C(C=C4)C#N)F)C#N

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