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PF-543 Citrate

SphK1 抑制剂

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产品目录号: A15210

库存状态:中国现货中国现货

产品名 目录号 价格 数量
PF-543 Citrate 5mg A15210-5
¥ 1,100.00
PF-543 Citrate 10mg A15210-10
¥ 1,900.00
PF-543 Citrate 50mg A15210-50
¥ 7,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

PF-543 Citrate is a novel cell-permeant inhibitor of SphK1 with a K(i) of 3.6 nM, PF-543 is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2 isoform.

PF-543 Citrate

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Chemical Information

目录号 A15210
Mechanism of action Inhibitor
分子量 657.73
化学分子式 C33H39NO11S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1415562-83-2
Synonyms PF543 Citrate, PF 543 Citrate
SMILES code CC1=CC(=CC(=C1)OCC2=CC=C(C=C2)CN3CCCC3CO)CS(=O)(=O)C4=CC=CC=C4.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
化学名称 [(2R)-1-[[4-[[3-(benzenesulfonylmethyl)-5-methylphenoxy]methyl]phenyl]methyl]pyrrolidin-2-yl]methanol;2-hydroxypropane-1,2,3-tricarboxylic acid

生物活性

Description
PF-543 Citrate is a novel cell-permeant inhibitor of SphK1 with a K(i) of 3.6 nM, PF-543 is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2 isoform.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.2 mL 76.02 mL 152.04mL
0.5 mM 3.04 mL 15.2 mL 30.41 mL
1 mM 1.52 mL 7.6 mL 15.2 mL
5 mM 0.3 mL 1.52 mL 3.04 mL

*The above data is based on the productmolecular weight 657.73. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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