PF-543

目录号: A13039

SphK1 inhibitor

PF-543

PF-543 Chemical Structure

CAS NO. 1415562-82-1

PF-543 is a novel selective SK-1 inhibitor which inhibited SK-1 activity in a competitive manner with sphingosine.

库存: 现货

规格 价格 数量
10 mg
¥ 1,500.00
25 mg
¥ 3,000.00
50 mg
¥ 5,000.00
10mM * 1mL in DMSO
¥ 1,290.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

PF-543 is a novel selective SK-1 inhibitor which inhibited SK-1 activity in a competitive manner with sphingosine.
Targets
SphK1 SphK1
2.0 nM3.6 nM(Ki)
In vitro DMSO 93 mg/mL (199.74 mM)
Water <1 mg/mL (<1 mM)
Ethanol 93 mg/mL (199.74 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.48 mL 107.39 mL 214.78 mL
0.5 mM 4.3 mL 21.48 mL 42.96 mL
1 mM 2.15 mL 10.74 mL 21.48 mL
5 mM 0.43 mL 2.15 mL 4.3 mL

*The above data is based on the productmolecular weight 465.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A13039
MECHANISM OF ACTION Inhibitor
M. Wt 465.6
Formula C27H31NO4S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1415562-82-1
Synonyms PF543,PF 543
SMILES CC1=CC(=CC(=C1)OCC2=CC=C(C=C2)CN3CCC[C@@H]3CO)CS(=O)(=O)C4=CC=CC=C4

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