PF 573228

目录号: A11235

FAK Inhibitor

PF 573228 Chemical Structure

CAS NO. 869288-64-2

PF 573228 is a potent and selective inhibitor of focal adhesion kinase (FAK) (IC50 = 4 nM).

库存: 现货

规格 价格 数量
10 mg
¥ 800.00
25 mg
¥ 1,500.00
50 mg
¥ 2,500.00
100 mg
¥ 4,000.00
10mM * 1mL in DMSO
¥ 980.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

PF 573228 is a potent and selective inhibitor of focal adhesion kinase (FAK) (IC50 = 4 nM).
靶点信息
FAK (Cell-free assay)
4 nM
In vitro (25°C) DMSO 26 mg/mL (52.9 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.35 mL 101.73 mL 203.46 mL
0.5 mM 4.07 mL 20.35 mL 40.69 mL
1 mM 2.03 mL 10.17 mL 20.35 mL
5 mM 0.41 mL 2.03 mL 4.07 mL

*The above data is based on the productmolecular weight 491.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11235
MECHANISM OF ACTION Inhibitor
M. Wt 491.5
Formula C22H20F3N5O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 869288-64-2
Synonyms PF-573228, PF573228
SMILES CS(=O)(=O)C1=CC=CC(=C1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)CC4

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