PF 670462

Name: PF 670462
SKU: A11781

目录号: A11781

Casein kinase 抑制剂

PF 670462 Chemical Structure

CAS NO. 950912-80-8

PF-670462是有效的、选择性CK1ε和CK1δ抑制剂，IC50分别为7.7和14 nM，其选择性是其他42种常见激酶的30倍以上。

库存：现货

规格	价格	数量
10 mg	￥ 1,100.00
25 mg	￥ 2,200.00
50 mg	￥ 4,050.00
100 mg	￥ 7,000.00

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生物活性

PF-670462是有效的、选择性CK1ε和CK1δ抑制剂，IC50分别为7.7和14 nM，其选择性是其他42种常见激酶的30倍以上。

溶解度 *

In vitro	DMSO	80 mg/mL (194.97 mM)
	Water	80 mg/mL (194.97 mM)
	Ethanol	27 mg/mL (65.79 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.37 mL	121.86 mL	243.72 mL
0.5 mM	4.87 mL	24.37 mL	48.74 mL
1 mM	2.44 mL	12.19 mL	24.37 mL
5 mM	0.49 mL	2.44 mL	4.87 mL

*The above data is based on the productmolecular weight 410.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11781
作用机制	Inhibitor (抑制剂)
M. Wt	410.3
Formula	C19H20FN5.2HCl
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	950912-80-8
Synonyms	PF670462
SMILES	C1CCC(CC1)N2C=NC(=C2C3=NC(=NC=C3)N)C4=CC=C(C=C4)F.Cl.Cl