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Autotaxin 抑制剂

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产品目录号: A11527


产品名 目录号 价格 数量
PF-8380 5mg A11527-5
¥ 640.00
PF-8380 10mg A11527-10
¥ 1,100.00
PF-8380 25mg A11527-25
¥ 2,500.00



PF-8380 is a potent and specific autotaxin inhibitor with an IC50 value of 2.8 nM.





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Chemical Information

目录号 A11527
Mechanism of action Inhibitor
分子量 478.33
化学分子式 C22H21Cl2N3O5
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1144035-53-9
Synonyms PF 8380, PF8380
SMILES code C1CN(CCN1CCC(=O)C2=CC3=C(C=C2)NC(=O)O3)C(=O)OCC4=CC(=CC(=C4)Cl)Cl
化学名称 3,5-dichlorobenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate


PF-8380 is a potent and specific autotaxin inhibitor with an IC50 value of 2.8 nM.
2.8 nM


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.91 mL 104.53 mL 209.06mL
0.5 mM 4.18 mL 20.91 mL 41.81 mL
1 mM 2.09 mL 10.45 mL 20.91 mL
5 mM 0.42 mL 2.09 mL 4.18 mL

*The above data is based on the productmolecular weight 478.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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