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PF-8380

Autotaxin 抑制剂

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产品目录号: A11527

库存状态:中国现货中国现货

产品名 目录号 价格 数量
PF-8380 5mg A11527-5
¥ 640.00
PF-8380 10mg A11527-10
¥ 1,100.00
PF-8380 25mg A11527-25
¥ 2,500.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

PF-8380 is a potent and specific autotaxin inhibitor with an IC50 value of 2.8 nM.

PF-8380

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Chemical Information

目录号 A11527
Mechanism of action Inhibitor
分子量 478.33
化学分子式 C22H21Cl2N3O5
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1144035-53-9
Synonyms PF 8380, PF8380
SMILES code C1CN(CCN1CCC(=O)C2=CC3=C(C=C2)NC(=O)O3)C(=O)OCC4=CC(=CC(=C4)Cl)Cl
化学名称 3,5-dichlorobenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate

生物活性

Description
PF-8380 is a potent and specific autotaxin inhibitor with an IC50 value of 2.8 nM.
Targets
Autotaxin
2.8 nM

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.91 mL 104.53 mL 209.06mL
0.5 mM 4.18 mL 20.91 mL 41.81 mL
1 mM 2.09 mL 10.45 mL 20.91 mL
5 mM 0.42 mL 2.09 mL 4.18 mL

*The above data is based on the productmolecular weight 478.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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