PF-8380

目录号: A11527

Autotaxin 抑制剂

PF-8380

PF-8380 Chemical Structure

CAS NO. 1144035-53-9

PF-8380是一种强效和特异的自动调节蛋白抑制剂,IC50值为2.8 nM。

库存: 现货

规格 价格 数量
5 mg
¥ 550.00
10 mg
¥ 800.00
25 mg
¥ 1,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

PF-8380是一种强效和特异的自动调节蛋白抑制剂,IC50值为2.8 nM。
靶点信息
Autotaxin
2.8 nM
In vitro (25°C) DMSO 89 mg/mL (186.06 mM)
Water Insoluble
Ethanol Insoluble
In vivo 1%cmc-na 14 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.91 mL 104.53 mL 209.06 mL
0.5 mM 4.18 mL 20.91 mL 41.81 mL
1 mM 2.09 mL 10.45 mL 20.91 mL
5 mM 0.42 mL 2.09 mL 4.18 mL

*The above data is based on the productmolecular weight 478.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11527
作用机制 Inhibitor (抑制剂)
M. Wt 478.33
Formula C22H21Cl2N3O5
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1144035-53-9
Synonyms PF 8380, PF8380
SMILES C1CN(CCN1CCC(=O)C2=CC3=C(C=C2)NC(=O)O3)C(=O)OCC4=CC(=CC(=C4)Cl)Cl

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