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PF-915275

PF-915275

Name: PF-915275
SKU: A21330

目录号: A21330

11βHSD1 inhibitor

PF-915275 Chemical Structure

CAS NO. 857290-04-1

PF-915275 is a potent, selective and orally active human 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) inhibitor with a Ki of 2.3 nM and an EC50 of 15 nM (in HEK293 cells).

库存：现货

规格	价格	数量
5 mg	￥ 970.00
10 mg	￥ 1,670.00
50 mg	￥ 4,970.00
100 mg	￥ 9,940.00

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生物活性

PF-915275 is a potent, selective and orally active human 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) inhibitor with a Ki of 2.3 nM and an EC50 of 15 nM (in HEK293 cells).

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	28.54 mL	142.7 mL	285.4 mL
0.5 mM	5.71 mL	28.54 mL	57.08 mL
1 mM	2.85 mL	14.27 mL	28.54 mL
5 mM	0.57 mL	2.85 mL	5.71 mL

*The above data is based on the productmolecular weight 350.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A21330
作用机制	Inhibitor (抑制剂)
M. Wt	350.39
Formula	C18H14N4O2S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	857290-04-1
SMILES	N#CC1=CC=C(C2=CC=C(S(NC3=NC(N)=CC=C3)(=O)=O)C=C2)C=C1