PF-AKT400

目录号: A21991

Akt inhibitor

PF-AKT400

PF-AKT400 Chemical Structure

CAS NO. 1004990-28-6

PF-AKT400 is a broadly selective, potent, ATP-competitive Akt inhibitor, displays 900-fold greater selectivity for PKBα (IC50=0.5 nM) than PKA (IC50=450 nM).

库存: 现货

规格 价格 数量
5 mg
¥ 3,780.00
10 mg
¥ 6,510.00
50 mg
¥ 19,320.00
100 mg
¥ 38,640.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

PF-AKT400 is a broadly selective, potent, ATP-competitive Akt inhibitor, displays 900-fold greater selectivity for PKBα (IC50=0.5 nM) than PKA (IC50=450 nM).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.97 mL 124.87 mL 249.73 mL
0.5 mM 4.99 mL 24.97 mL 49.95 mL
1 mM 2.5 mL 12.49 mL 24.97 mL
5 mM 0.5 mL 2.5 mL 4.99 mL

*The above data is based on the productmolecular weight 400.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A21991
作用机制 Inhibitor (抑制剂)
M. Wt 400.43
Formula C20H22F2N6O
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1004990-28-6
Synonyms AKT protein kinase inhibitor; PF-AKT400; PFAKT400; Lig1; Lig-1; Lig 1; PF AKT400; AKT-0286; AKT 0286; AKT0286
SMILES N[C@@](CC1)(CNC(C2=CC=C(F)C=C2F)=O)CN1C3=C4C(NC=C4CC)=NC=N3

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