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PF-CBP1

CREBBP 抑制剂

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产品目录号: A15876

库存状态:中国现货中国现货

产品名 目录号 价格 数量
PF-CBP1 10mg A15876-10
¥ 800.00
PF-CBP1 25mg A15876-25
¥ 1,800.00
PF-CBP1 50mg A15876-50
¥ 3,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

PF-CBP1 is a highly selective inhibitor of the bromodomain of CREB-binding protein(CREBBP).It inhibits CREBBP and p300 bromodomains with IC50 of 125 and 363 nM respectively.

PF-CBP1

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Chemical Information

目录号 A15876
Mechanism of action Inhibitor
分子量 525.08
化学分子式 C29H36N4O3.HCl
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. PF-CBP1
Synonyms PF-CBP-1, PF-CBP 1, PF-06670910, PF 06670910, PF06670910
SMILES code CCCOC1=CC=C(CCC2=NC3=CC(C4=C(C)ON=C4C)=CC=C3N2CCN5CCOCC5)C=C1
化学名称 5-(Dimethyl-1,2-oxazol-4-yl)-1-[2-(morpholin-4-yl)ethyl]-2-[2-(4-propoxyphenyl)ethyl]-1H-1,3-benzodiazole hydrochloride

生物活性

Description
PF-CBP1 is a highly selective inhibitor of the bromodomain of CREB-binding protein(CREBBP).It inhibits CREBBP and p300 bromodomains with IC50 of 125 and 363 nM respectively.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.04 mL 95.22 mL 190.45mL
0.5 mM 3.81 mL 19.04 mL 38.09 mL
1 mM 1.9 mL 9.52 mL 19.04 mL
5 mM 0.38 mL 1.9 mL 3.81 mL

*The above data is based on the productmolecular weight 525.08. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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