|EGFR (Cell-free assay)||ErbB2 (Cell-free assay)||ErbB4 (Cell-free assay)|
|6.0 nM||45.7 nM||73.7 nM|
|In vitro (25°C)||DMSO||19 mg/mL (40.43 mM)|
|Water||<1 mg/mL (<1 mM)|
|Ethanol||<1 mg/mL (<1 mM)|
|In vivo||1% DMSO/30% polyethylene glycol/1% Tween 80, pH 9||10 mg/mL|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||21.28 mL||106.41 mL||212.81 mL|
|0.5 mM||4.26 mL||21.28 mL||42.56 mL|
|1 mM||2.13 mL||10.64 mL||21.28 mL|
|5 mM||0.43 mL||2.13 mL||4.26 mL|
*The above data is based on the productmolecular weight 469.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|MECHANISM OF ACTION||Inhibitor|
|Storage||at -20°C 3 years Powder|
|Synonyms||PF-299804, Dacomitinib, PF-299|
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