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PFI-2

目录号: A14216
SETD7 抑制剂
PFI-2 是一种强效、选择性且在细胞内活跃的赖氨酸甲基转移酶SETD7抑制剂,其Ki (app) 和 IC50 分别为0.33 nM 和 2 nM,对其他甲基转移酶和非表观遗传靶标具有1000倍的选择性。
Grouped product items
规格 价格 库存 数量
5mg
¥525.00
现货
10mg
¥875.00
现货
25mg
¥1,610.00
现货
50mg
¥2,940.00
现货
100mg
¥5,600.00
现货
10mM * 1mL in DMSO
¥735.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription PFI-2 is a potent, selective, and cell-active lysine methyltransferase SETD7 inhibitor with Ki (app) and IC50 of 0.33 nM and 2 nM, 1000-fold selectivity over other methyltransferases and other non-epigenetic targets.
Targets
Target Value
产品信息
目录号 A14216
分子式 C23H25F4N3O3S
分子量 499.52
CAS号 1627676-59-8
SMILES C1CCN(C1)C(=O)[C@@H](CC2=CC(=CC=C2)C(F)(F)F)NS(=O)(=O)C3=CC(=C4CNCCC4=C3)F
其他名称 PFI2
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

  • Calculator Reset
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